
Walter Isaacson, University Professor of History at Tulane, has been CEO of the Aspen Institute, chairman of CNN, and editor of Time magazine. He is the author of “Leonardo da Vinci;” “Steve Jobs;” “Einstein: His Life and Universe;” “Benjamin Franklin: An American Life;” and “Kissinger: A Biography.” He is also the coauthor of “The Wise Men: Six Friends and the World They Made.” His new book “The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race,” is a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies. It will be released Tuesday, March 9, 2021. Excerpt available here. (amazon, 2021)
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled “The Double Helix” on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls did not become scientists, she decided she would.
Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform humanity: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.
The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
After helping to discover CRISPR, Doudna became a leader in wrestling with the moral issues that come along with it and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.

